Featured APS New Member 


David Hunstad, MD, is Chief of the Division of Pediatric Infectious Diseases and Associate Professor of Pediatrics and Molecular Microbiology at Washington University. He received his medical training at Washington University School of Medicine in 1995 and completed fellowship training in 2003. His primary research interest is in the interactions of Gram-negative bacterial pathogens with their hosts, using Escherichia coli urinary tract infections (UTI) as his primary model system. His laboratory has employed both murine and in vitro models to study outer membrane protein assembly and virulence contribution in uropathogenic E. coli (UPEC), and to reveal mechanisms by which uropathogenic bacteria modulate host immune responses during bacterial cystitis.

More recently, his research group developed a new mini-surgical murine model of cystitis and pyelonephritis that, for the first time, permits direct examination of sex and gender differences in UTI pathogenesis and host responses. His fellowship work was supported by the Pediatric Scientist Development Program, and his early independent studies were funded by the March of Dimes, Mallinckrodt Foundation, and NIDDK. He has served as principal investigator on multiple NIH R01 grants and within the framework of a large P50 program grant from the NIH Office of Research on Women's Health. Beyond these activities, Dr. Hunstad is committed to the mentoring and training of pediatric physician-scientists. Before assuming the division chief role, he was Pediatric ID fellowship director for six years. He currently serves as Pediatric Co-director of the Oliver Langenberg Physician-Scientist Training Program at Washington University, which provides selected MD/PhD pediatric residents and fellows with enhanced mentoring, resources, and opportunities en route to successful investigative careers in academic pediatrics. He is also Program Director for the Child Health Research Center of Excellence (K12) at Washington University and a mentor on multiple NIH T32 training grants.


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